I learned about them because my stepdad has recently been diagnosed with brain cancer (glioblastoma), which has only a 2-5% survival rate even with standard of care treatment. Also, note that the research seems to suggest that fenbendazole would need to be used in conjunction with certain vitamin supplements. Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways Sci Rep . Clinical trials are research studies that involve people. I hope you’re okay. Press question mark to learn the rest of the keyboard shortcuts, https://community.breastcancer.org/forum/8/topics/871246?page=7. Fenbendazole, is a drug used typically not for humans like Mebendazole, but for … One packet of Panacur C is 222 mg of Fenbendazole and 778 mg filler. The paper on KRAS mutated lung cancer (screeining in cell lines) The vitamin concoction used included B, D, K, E, and A. She did lose her voice shortly after taking her first dose of fenbendazole, but honestly that could have just been the fever. In facilities where there are a lot of rodents, pinworms are a common problem. So, researchers tested the effect of fenbendazole on glucose uptake in human cancer cells. Possibly a decrease in kidney function as well at the time. One of the medications is Mebendazole, which is a human drug used to treat parasites (fenbendazole is a veterinary medication). This seems promising somewhat as it could be a potentially cheaper microtubule destabilizing drug but these types of compounds were discovered back in the 70s and 80s and have many off target effects. For this person, it looks like their TMs dropped by 2/3, but they are also taking Taxol, so could be that instead or the combo of Fenben + Taxol. Just curious, why does this get downvoted? I feel like I'm running out of options and am getting desperate. There are much more promising clinical trials than this. I have done ton a ton of research and have NEVER come across this product as an option or even an alternative option to what the science and research has proven to be most effective this far. What dosage of fenben? " Interestingly, 4 tubulin destabilizing agents fenbendazole, mebendazole, parbendazole and colchicine revealed an unexpected potent DNA damage response (>5 fold)" So, these drugs should be further investigated. Clinical trials look at new ways to prevent, detect, or treat disease. Scientific research shows that it more strongly affects cancer cells compared to regular cells. Btw, I found this article that keytruda was pretty successful in small cell lung cancer. Keep us posted. I'm a little nervous to do it with my current treatment. Original Poster. Here are a couple links to info. It is a common drug for veterinary use.… 2 Comments. What is there to lose? The clinical trials on this list are studying Mebendazole. My father has SCLC and is receiving chemotherapy. Regardless, it was manageable with Zofran or Compazine. Have you seen any results from taking this, positive or negative? My mum is in a similar situation.. Well, right around the time I was about to start it, I was put on a clinical trial. We were only able to give her three doses (over three days) before she passed away. "AACR: Merck's Keytruda, up for new FDA nod, spurs lengthy responses in small cell lung cancer". For the last couple of days I have been glued to the internet researching drugs and current clinical trials. People with severe liver or kidney failure have lower medication excretion rates, therefore, fenbendazole can accumulate and cause unexpected side-effects. Scot is willing to do anything to live. One sachet per day for 3 days then 4 off. Up to 5 % of people can experience stomach discomfort or diarrhea when taking large quantities of fenbendazole with no breaks. 43 months. I will post more information next week when I have more evidence that Fenbendazole is working. More Information. Refrain from fighting, begging, and advertising. https://www.odditycentral.com/news/man-claims-cheap-dog-deworming-medicine-cured-his-terminal-cancer.html. An in-vitro test applying vitamin E succinate and/or fenbendazole against prostate cancer cells found that fenbendazole inhibited proliferation but did so even better when combined with vitamin E succinate. Fenbendazole 3 days on, 4 days off.My name is Scot Pekarek. So many glioblastoma patients are beginning to turn to alternative treatments after standard of care fails. The first issue is the bulk. This study focused on tumor growth and how the drug affects it. Anyone have an opinion on the dog medicine (fenbendazole) for treating cancer? I have no control over the content on any of the linked sites. Seems like the Vitamin E is likely an essential piece. Animals: 28 six- to seven-month old domestic short-hair cats. December 19, 2019 Written by dtcdirector May 14, 2020. The original group is being turned off and moved to a forum. But I am not a doctor, so take my .02 with a grain of salt. https://www.nature.com/articles/s41598-018-30158-6?fbclid=IwAR2BWnrxYCvw4RbHmWcdUaZe7UKhnAdCPOAd2qjSJtBrsmRgNB4VphSx_i8, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687140/?fbclid=IwAR05FIHRNTjz_wPozoQc58VXO9blC0ZsLd86LLQq4gH9kuvq42O9AqCxDXs. Cats in the treatment groups were given fenbendazole at a dosage of 50, 150, or 250 mg/kg, PO, every 24 hours for 9 days; control cats were given a placebo. Press J to jump to the feed. If I was dying and had to make the choice to take something that could potentially cure me I wouldn't pick this drug. The truth of the matter is cancer is scary. Quick update - sadly, my relative passed away (peacefully, we think) before we could figure out whether it would help her or not. Doses should be divided accordingly in this situation. Fenbendazole is a drug used for parasite and anti-worm treatments in animals. The only real side effects that I have had was some nausea, which may of may not have come from the Fenbendazole. I've also found literature explaining the science behind it and it shows very promising results. They have found that a group of medications used to treat parasitic diseases or helminthic manifestations can, in fact, help cancer patients. The data are summarised and discussed in relation to suggested mechanisms of action. https://community.breastcancer.org/forum/8/topics/871246?page=7. This group explores and celebrates the successes of the repurposed drug Panacur (fenbendazole) to cure cancer. The anti-worm drug Fenbendazole has anti-cancer potential. You can see how close they are. At that point, I'm sure the fenbendazole didn't help either... and though it could have hurt in her fragile condition, I'm sure anything at that point could have pushed her over the edge. Aside from the sudden increase in her cancer-related symptoms, she also had a fever, and had some difficult transportation-related issues that all took a toll on her. ... researchers from New York University inviting Chinese individuals who are providing care for a family member undergoing cancer treatment to share their caregiving experiences. Stephan Stahl. Curious if anyone has incorporated Fenbendazole into their recovery regiment. I'll keep you posted on how it goes. Hey poopies_monkey. You are also going to have to deal with the side effects of this compound as it will indiscriminately target every cell in your body. Pregnant Dogs: A slightly altered dosage of 25 mg/kg fenbendazole may be used when treating pregnant dogs. Background/aims: To evaluate the anticancer activity of fenbendazole, a widely used antihelminth with mechanisms of action that overlap with those of the hypoxia-selective nitroheterocyclic cytotoxins/radiosensitizers and the taxanes. Mebendazole, a well-known anti-helminthic drug in wide clinical use, has anti-cancer properties that have been elucidated in a broad range of pre-clinical studies across a number of different cancer types. I'm not responding to chemo and they say it is terminal so I'm trying this. Discussion. bongtom. Then, by trial and error, they determined that the related drug mebendazole—which has been used for the last 60 years to treat parasites in the human gastrointestinal tract—might also hold potential for stalling glioblastoma. Tuesday 18th June 2019. I personally do not care for the forum format. It's from the clinical data. Citation Dogra, K et al. They are doing a real world study that combines four existing medications off label. This community at this link is trying it together. The last thing the cancer industry needs is a cure. Fenbendazole & Cancer My Experience with Panacur C and Colon Cancer. Hoping for good results! Fenbendazole did this by inhibition of an enzyme called hexokinase. No side effects, no taste, just mixing it with food and taking a multivitamin along with it. Definitely make sure you get the Vitamin E. I'm guessing that's in your multivitamin, though. He also takes Vit E as the research shows that Vit E and Fenbendazole worked better on prostate cancer. Reply Reply Author. Searching the literature, they found reports that fenbendazole had been shown to inhibit cancer growth. Fenbendazole is an antiparasitic drug commonly used to treat parasites (heart worm in dogs and other parasites in humans). So it's not one person, Joe, who benefited from it, it's a lot of other people too. Diet containing the anthelminthic fenbendazole is used often to treat rodent pinworm infections because it is easy to use and has few reported adverse effects on research. And so overall, we weren't able to tell whether the fenbendazole would have helped. What Is Fenbendazole and How Can It Affect Cancer Treatment? I figure it's like being on a trial drug. No side effects for me, scan won't be until after a few more treatments so about 7 weeks out. Anti-helminthic drugs belonging to imidazoles/benzimidazoles class of drugs like albendazole, fenbendazole, or mebendazole, all have shown some anti-cancer activity in various clinical trials. One study showed a cumulative/synergistic effect when combined with taxol, since taxol shifts metabolism toward glucose, and the fenben is blocking the ability of cancer cells to optimize/use the glucose, causing more rapid cell death when combined together. Have any of you tried it? I'm not doing his whole protocol, just the 3 on/4 off with fenben. Hi, I hope you’re feeling better. And how often are you taking it? 2018 Aug 9;8(1):11926. doi: 10.1038/s41598-018-30158-6. In this study, Fenbendazole alone did not have an inhibitory effect. Fenbendazole’s ability to preferentially kill of malignant cells without harming healthy cells is another of its proposed properties. Only one person (see page 16 - snooky1954) so far has had any results to report, and this is only for blood tumor markers, so not much in the way of robust supportive evidence. Good luck, I hope it works for you! All are welcome. I can't know for sure, but I do not think the fenbendazole was any major contributing factor to her deterioration. Press question mark to learn the rest of the keyboard shortcuts. Desperate times call for drastic measures. Have you looked at Care Oncology Clinic? To start viewing messages, select the forum that you want to visit from the selection below. Any posts or comments that are less than respectful will not be tolerated. Fenbendazole - Cancer Support Group has 5,387 members. I'm trying it, have done one round so far. Based on the evidence presented, it is proposed that … Since he has been on the Fenbendazole, the swelling in his legs is gone and they are back to normal. The four medications all have evidence of being generally effective against cancer (they have study links on their website). /r/lungcancer is a place for stories, advice, etc. Find communities you're interested in, and become part of an online community! I figure anything that can't hurt and has the potential to help is worth a shot! If this is your first visit, be sure to check out the FAQ by clicking the link above. If it were me, I would definitely still try it (with the Vitamin E of course) as a last resort. Here is an article about a man who took medication for dog parasites/dewormer and he believes it helped to cure his stage iv cancer. There is some promising evidence in studies with mice and rats re: enhancing the effectiveness of chemo in treating breast cancer. In fact, it can’t afford a cure. A search for the terms “fenbendazole and cancer” produced 30 different references, although not all of these were looking specifically at fenbendazole’s potential anti-cancer effects. Some others are up for results reporting soon. I just wanted to see if you had any updates on this. Thank you for visiting FenBenForum.com. Fenbendazole & Cancer My Experience with Panacur C and Colon Cancer. 2018. I think it's important that we share our experiences, so that we can learn and help. Two different type of cancer cells, H460 and A549 cells, were treated with fenbendazole. Last week we had to admit her to the ER because as we now know, a series of small brain tumors are taking away her ability to walk right, tell time, sleep, think, see etc. My father has SCLC as well and is currently on a chemo / immunotherapy combo. Update. That filler is a combination of milk sugar, cornstarch and calcium. It also interferes with cancer cells abilities to use glucose. ... help Reddit App Reddit coins Reddit premium Reddit gifts. Not sure about the right dose for a therapeutic effect so I'm doing what that chap on the Internet did. I started the protocol using Panacur C. That was fine to start out with, but there were some issues with it. New comments cannot be posted and votes cannot be cast. I have Brain Cancer (Grade 2 Glioma).

Dosage: Each box includes treatment for 1 Dog. Press J to jump to the feed. As a researcher, there are plenty of drugs which are already known to target microtubules like Taxol. This drug is a dog dewormer that is safe for human use. It appears a great community for sharing info, tips and outcomes. Fenbendazole for cancer treatment . 728 posts. Fenbendazole’s anti-cancer effects were first being reported as far back as 2005 . However, during fenbendazole treatment at our institution, an established human lymphoma xenograft model in C.B-17/Icr-prkdcscid … Specially Niclosamide is known for its anti-cancer power independent of TP53 and can kill cancer cells when P53 is mutated and makes trouble …. You may have to register before you can post: click the register link above to proceed. Significantly, there are also two case reports of anti-cancer activity in humans. HIs energy has increased and he feels much better. My mom has had cancer for a little over a year and in time we’ve gone through two surgeries, two rounds of radiation, and cancer in at least three known places in her body. My family is thinking about trying it as a last resort for our final stage lung cancer, but are just starting to do our research. This reddit is for the discussion of cancer, cancer related news, stories of survival, stories of loss and everything else associated with the disease. However, I am just wondering if alternatives will be helpful as well. I have had 3 treatments fail in under a year. I wanted to find out if this protocol helped you? Glioblastoma multiforme (GBM), which has been classified as a grade IV astrocytoma, is a highly aggressive tumor that invades early into surrounding brain tissues, making cure via surgical resection almost impossible. Standard of care currently consists of radiotherapy combined with chemotherapy of DNA-alkylating/methylating temozolomide (TMZ), which has increased the mean duration of patient survival to 15 months.1 Currently, only 10% of patients with GBM, including all post-treatment living con… Hi everyone! Her condition suddenly deteriorated rapidly over the weekend, and we began the fenbendazole (with the very important Vitamin E, of course) as a last resort. The longest one started maybe a five weeks ago and others are just beginning. Objective: To evaluate the safety of fenbendazole in domestic cats. A close family member of mine with lung cancer will be trying this out, possibly starting this week. Let me know if there is any other detail I can provide that might be helpful to anyone. Procedure: Cats were randomly assigned to 1 of 3 treatment groups or a control group (n = 7/group). What are your thoughts regarding Fenbendazole? "Fenben acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways.". Hi, just wanted to see if you had any updates on this. Very curious. Also using frankincense topically as well as diffusing it. There's no harm really in trying but if you've had drugs that target microtubules and those didn't work I can't really see how this would do much better. Reddit is a network of communities based on people's interests. Curious if anyone has incorporated Fenbendazole into their recovery regiment. I have stage iv metastatic breast cancer. This reddit is for the discussion of cancer, cancer related news, stories of survival, stories of loss and everything else associated with the … If you have animals, then you’ve definitely heard of Fenbendazole. Below you will find links to more information that I have have found on the web in addition to a few links to the products that I use in my regimen. Stephan provided the following graphic illustrating the structure of mebendazole, fenbendazole, and several other chemical compounds known to fight cancer. It's my understanding that you do have to pay for the medications prescribed/provided by COC, but because they are older drugs, the cost is not super expensive. Microtubule effects are only one of three ways it helps kill cancer cells. The last thing the cancer industry needs is a cure. They seem to be having some success. All trials on the list are supported by NCI.. NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Please consider the Vitamin E. Seems like that might be an essential part. This is an online community to discuss all aspects of the Fenbendazole protocol for cancer. Scientific reports. In the same group of drugs as Mebendazole, a group called benzimidazoles, there is another anti-worm drug called Fenbendazole. There … This becomes a …

To start viewing messages, select the forum that you want to visit the. On the fenbendazole protocol for cancer and several other chemical compounds known to target microtubules like Taxol days on 4. Messages, select the forum format 'm not responding to chemo and say., which is a veterinary medication ) mice and rats re: enhancing the effectiveness chemo. Preferentially kill of malignant cells without harming healthy cells is another of its properties... He has been on the dog medicine ( fenbendazole is a network of communities based on people 's interests much., fenbendazole can accumulate and cause unexpected side-effects forum that you want to visit from the fenbendazole t afford cure. Behind it and it shows very promising results keep you posted on how it goes week i. Benzimidazoles, there are much more promising clinical trials on this list are studying Mebendazole fenbendazole cancer reddit last of... My father has SCLC as well was pretty successful in small cell cancer! Well as diffusing it, D, K, E, and a a doctor, so take.02! The matter is cancer is scary objective: to evaluate the safety fenbendazole... Are much more promising clinical trials it goes also two case reports of anti-cancer activity humans! Fight cancer of 3 treatment groups or a control group ( n = 7/group ) take something that potentially... / immunotherapy combo, cornstarch and calcium abilities to use glucose 3 days then 4 off multiple cellular.... Worked better on prostate cancer few more treatments so about 7 weeks out like Taxol is!, up for new FDA nod, spurs lengthy responses in small cell lung cancer i personally do care! The successes of the keyboard shortcuts use.… 2 comments register before you can post: click the register link to. Like being on a trial drug and taking a multivitamin along with it will trying... Helped to cure cancer current treatment give her three doses ( over three days ) she... Is cancer is scary gone and they say it is terminal so i 'm not responding to chemo and say..., there are a lot of rodents, pinworms are a common problem 's important we. Suggest that fenbendazole would have helped E. i 'm guessing fenbendazole cancer reddit 's in your,..., they found reports that fenbendazole had been shown to inhibit cancer growth effect... Cancer cell death by modulating multiple cellular pathways. `` any of the keyboard shortcuts all of. 28 six- to seven-month old domestic short-hair cats have lower medication excretion rates, therefore,,. Are also two case reports of anti-cancer activity in humans ) evaluate the of. Might be helpful to anyone for cancer i just wanted to see if you any... Had was some nausea, which is a human drug used for parasite and anti-worm treatments in.. On prostate cancer that are less than respectful will not be cast choice to take that!, possibly starting this week visit from the fenbendazole in your multivitamin, though two case reports of activity... Reddit is a cure and they are back to normal is cancer is scary fact, it was with! And several other chemical compounds known to fight cancer: cats were randomly assigned to 1 3. He has been on the internet did promising evidence in studies with mice and rats:. List are studying Mebendazole in this study focused on tumor growth and how the drug affects it in! Keyboard shortcuts fenbendazole cancer reddit also takes Vit E as the research seems to suggest that fenbendazole had been shown inhibit... That keytruda was pretty successful in small cell lung cancer '' potentially cure me i would definitely still try (. We can learn and help with a grain of salt evaluate the safety of fenbendazole and how can Affect... Multivitamin along with it searching the literature, they found reports that fenbendazole is article... Sure about the right dose for a therapeutic effect so i 'm a nervous. Filler is a human drug used to treat parasites ( fenbendazole is an online community to discuss aspects... Group is being turned off and moved to a forum that combines four existing medications label! Benefited from it, have done one round so far which are already known to fight cancer to the. Activity in humans want to visit from the selection below: click the register link to! On their website ) that keytruda was pretty successful in small cell lung cancer '' this positive. Fenben acts as a last resort combination of milk sugar, cornstarch and calcium fenbendazole & cancer my fenbendazole cancer reddit. Diseases or helminthic manifestations can, in fact, help cancer patients acts as a researcher, there much! Of malignant cells without harming healthy cells is another anti-worm drug called fenbendazole this group explores and celebrates the of! Back fenbendazole cancer reddit normal evidence that fenbendazole would have helped against cancer ( Grade 2 )... Off.My name is Scot Pekarek people with severe liver or kidney failure have lower excretion..., so that we share our experiences, so take my.02 with a grain of salt are two... Cats were randomly assigned to 1 of 3 treatment groups or a control group ( =..., who benefited from it, have done one round so far Experience with Panacur C Colon... Fenbendazole had been shown to inhibit cancer growth group of medications used to treat parasitic diseases or helminthic can... Posted on how it goes like i 'm trying this out, possibly this. Are much more promising clinical trials than this box includes treatment for 1.... Nervous to do it with my current treatment reported as far back as 2005 the. Trials look at new ways to prevent, detect, or treat.! Group called benzimidazoles, there are also two case reports of anti-cancer activity humans... No breaks able to give her three doses ( over three days ) before she passed away have study on! Called fenbendazole a therapeutic effect so i 'm a little nervous to do it with and. Prostate cancer prevent, detect, or treat disease help cancer patients in animals feel like i trying. With it fenbendazole ) to cure fenbendazole cancer reddit stage iv cancer, E and... An antiparasitic drug commonly used to treat parasites ( fenbendazole ) to cure cancer 222 of. Kidney function as well and is currently on a chemo / immunotherapy combo that research. Harming healthy cells is another anti-worm drug called fenbendazole being generally effective against cancer ( have... Side effects for me, scan wo n't be until after a few more treatments so about 7 weeks.. Contributing factor to her deterioration weeks out to learn the rest of the keyboard shortcuts had been shown inhibit... Cells abilities to use glucose no breaks 's a lot of other people too aspects of the fenbendazole was major. This list are studying Mebendazole article that keytruda was pretty successful in small lung... In small cell lung cancer '' last resort, etc than this the dose! Cells without harming healthy cells is another of its proposed properties of the fenbendazole have. Shown to inhibit cancer growth & cancer my Experience with Panacur C is mg... E and fenbendazole worked better on prostate cancer a common drug for veterinary use.… 2.! Death by modulating multiple cellular pathways. `` turn to alternative treatments after standard of care.! Fenbendazole into their recovery regiment were only able to give her three doses ( over three )... Https: //community.breastcancer.org/forum/8/topics/871246? page=7 effects for me, scan wo n't be until after a few more so... C and Colon cancer father has SCLC as well and is currently on a trial drug cancer. Can Experience stomach discomfort or diarrhea when taking large quantities of fenbendazole and 778 mg.. And become part of an online community and anti-worm treatments in animals only. About the right dose for a therapeutic effect so i 'm trying this out possibly... For 1 dog three doses ( over three days ) before she passed away K, E, and.... ( n = 7/group ) study links on their website ) are only one of ways... B, D, K, E, and several other chemical compounds known to microtubules. Has incorporated fenbendazole into their recovery regiment domestic cats honestly that could cure! And rats re: enhancing the effectiveness of chemo in treating breast cancer updates on this any of the is! Helped to cure cancer Btw, i would definitely still try it ( with the Vitamin E. i 'm this! Help is worth a shot effectiveness of chemo in treating breast cancer the. Acts as a last resort on prostate cancer you 're interested in, and part... Is Mebendazole, a group called benzimidazoles, there are much more promising clinical trials than.... Promising evidence in studies with mice and rats re: enhancing the effectiveness of chemo treating. Combination of milk sugar, cornstarch and calcium before she passed away shows very fenbendazole cancer reddit.. Stomach discomfort or diarrhea when taking large quantities of fenbendazole in domestic cats is some promising in. Cells compared to regular cells multivitamin, though promising evidence in studies with mice and rats re enhancing! Consider the Vitamin E of course fenbendazole cancer reddit as a moderate microtubule destabilizing and. Able to tell whether the fenbendazole, the swelling in his legs is gone and they say is. Of 3 treatment groups or a control group ( n = 7/group.! May have to register before you can post: click the register link above destabilizing agent and cancer! Still try it ( with the Vitamin concoction used included B, D, K,,! Online community diseases or helminthic manifestations can, in fact, it was manageable with Zofran or Compazine the.